Used for centuries in traditional Chinese medicine, Rhodiola Rosea is the root of a high altitude plant known as Golden Root, Rose Root, or King’s Crown. When taken for supplementation, the root works as an adaptogen, bringing physical stress reactions and emotional states into balance. It also encourages AMPK enzymes, which help to boost cellular mitochondria’s methods of creating larger amounts of energy. The root also works as a MAO inhibitor, helping to regulate levels of serotonin and dopamine. In addition, Rhodiola Rosea works with the opioid peptide beta-endorphin to positively impact mood.

A few of its benefits include stress relief, a natural curb of depressive symptoms, and strong effects to lessen feelings of fatigue. Rhodiola Rosea induces heightened concentration and mental focus. It can enhance motivation while delivering the energy necessary to follow through at the same time.



Rhodiola Rosea acts through the stimulation of a specific class of enzymes known as AMPK. When the body has more of this enzyme, or they become more active, we end up having more mitochondria within our cells. Mitochondria are popularly referred to as the power plants of our cells.

Higher levels lead to more fat burning and an increased uptake of glucose into the muscle cells. More glucose leads to more metabolic activity, better cell functioning, and higher energy levels.

In addition, one of the of the main ingredients found within Rhodiola Rosea is called salidroside. This is primarily responsible for inducing muscle cells into absorbing more glucose. In this respect, it almost imitates the effect of insulin.

Not only that, but this active ingredient is also considered to be an effective insulin booster. Together, these work to increase the AMPK enzymes, creating a feedback loop of sorts.

Rhodiola Rosea also has several nootropic-specific mechanisms of action. It increases serotonin and dopamine levels found in the brain while simultaneously preventing their breakdown. The herbal extract is an MAO inhibitor, able to slow down the metabolization of the neurotransmitters serotonin and dopamine. It is further noted that Rhodiola Rosea can influence the opioid peptide beta-endorphin, which can lead to feelings of pleasure and well-being.

Side Effects & Dosages

While Rhodiola Rosea is considered to be a very safe and well-tolerated supplement, there are some side effects associated with its use. These are generally mild and similar to what would be expected from any type of mild stimulant, which can include anxiety, agitation, nausea, hypersalivation, restlessness, and insomnia. But when not abused, side effects are less likely.

The typical daily dosage range for Rhodiola Rosea is between 100 and 600 mg. Since Rhodiola Rosea is considered to be a mild stimulant it should be used and approached with caution.

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