Rasagiline was initially developed in the early 2000’s by an Israeli team of researchers who worked for Teva Pharmaceuticals Ltd (now Teva Pharmaceuticals Industries). It quickly became a common substance in the treatment of Parkinson’s disease after being introduced to the FDA in 2004, and has continued to be a primary factor in the fight against Parkinson’s throughout the world. Primarily, rasagiline works to influence the enhanced production of dopamine, a neurotransmitter critical in the body’s control of motor functions, mood, and motivation. Rasagiline prevents the enzyme MAO-B (Monoamine oxidase B) from breaking down dopamine within the central nervous system, effectively increasing and moderating its effect on the brain. This combats regular symptoms of Parkinson’s such as tremors and stiffness throughout the body. Rasagiline also functions as a capable antioxidant, protecting the brain from harmful toxins that could negatively affect nerve functions. A few examples include SIN-1 and Glutamate. However, Rasagiline is structurally similar to methamphetamine as it breaks down, and can even (although circumstances are extremely rare) lead to pathways that would normally be destructive, or relating to harmful effects on the cardiovascular system. It can also cause mental irregularities in people when used improperly.
Side Effects & Dosages
It is very difficult to develop a tolerance to Rasagiline, ensuring that the substance will continue to prove effective even after long periods of use. Taking it every day will not affect its potency on the central nervous system, although there are common side effects associated with its use. These include but are not limited to: headaches, drowsiness, dizziness, and joint pains. Uncommon allergic reactions can incite hives and/or a puffiness of the throat, tongue, or eyes. Mild cases of vertigo and hallucinations have also been reported. It should be stressed that Rasagiline is a powerful substance, and so its consumption should be correlated with the recommendation and advice from a qualified medical professional. Typical doses range from .5 and 1 mg daily, and increasing dosages is heavily discouraged, as actions such as those can lead to irregular problems and even death.