Developed in 1961, pyritinol is a vitamin naturally occurring in a variety of meats, vegetables, and fruits (which include poultry, chickpeas, and bananas). It encourages the absorption of choline by neurons in the brain. It is known to enhance the levels of both acetylcholine and dopamine to boost cognitive focus, learning, memory, and also to help elevate a user’s mood.



Once pyritinol crosses the blood brain barrier and reaches the brain, it acts as both a precursor to acetylcholine (a powerful neurotransmitter that is released by nerve cells to communicate with other cells) and dopamine (another neurotransmitter that helps to regulate a user’s motivation and stress levels). Because pyritinol’s chemical structure changes to become these compounds, it works to enhance their levels in the central nervous system, effectively boosting the brain’s ability to focus, feel pleasures that can positively affect an individual’s motivation, and store and process anything learned. It is often considered to be an enhanced version of the compound pyridoxine, which helps to boost its already commendable cognitive enhancement abilities when compared to it.

Side Effects

Pyritinol carries a few serious side effects, generally occurring in the circumstance of prolonged use. Recorded instances of major effects include the inflammation of the liver and the pancreas (hepatitis & pancreatitis), and minor side effects include but are not limited to: loss of appetite, fatigue, rashes and itchy skin, and diarrhea. It is important to contact a qualified physician at the first instance of any of these conditions.


Side effects from pyritinol come with prolonged use, so it is important to be as accurate as possible while consuming this supplement. Dosage ranges can fall in-between 100 to 1200 mg daily, which fluctuates depending on the reasons for use and disposition of the user. User dosages tend to fall in the 400 to 600 mg range, but a professional medical opinion will clarify any concerns regarding appropriate levels of consumption.

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