Also known as nicotinoyl-GABA, Pycamilon, and Pikamilon, Picamilon is made from a combination of niacin (Vitamin B3) and GABA (an inhibitor neurotransmitter). It is able to cross the blood-brain barrier by combining niacin with GABA, which is normally ineffective as a supplement due to its low bioavailability. Picamilon can boost cognitive functionality, sharpen mental focus, and lower anxiety and stress.



Picamilon was first developed in Russia in 1970 at the All-Union Vitamin Research Institute, where it was synthesized as a white, odorless, and crystalline powder that had the ability to capture moisture quite easily. GABA, one of its primary components, is responsible for relaxing an overly active brain, while Niacin (an ideal chemical partner) is able to cross the blood-brain barrier and enhance blood circulation, delivering more oxygen and nutrients (such as glucose, a natural energy source) to the organ.

Picamilon also has antioxidant properties (mainly due to the synergistic combination of GABA and Niacin), which helps the supplement to remove harmful toxins and poisons from brain cells. Energy metabolism is also enhanced, which directly leads to boosted levels of focus and mental endurance. In addition, evidence has surfaced that could lead to Picamilon being a reliable treatment in the prevention of both diabetic neuropathy and a condition called hypokinesia, although testing is still ongoing.

Side effects and Dosages

Picamilon is generally regarded as safe for daily use, with only rare cases of allergies and skin rashes as uncommon side effects. More common side effects can include headaches, nausea, low blood pressure, and irritability. Dosages typically fall in-between 50 to 400 mg daily, although initial amounts for consumption are recommended at 100 to 200 mg. A dosage opinion from a qualified medical professional should be taken into consideration in the instance when Picamilon would be strictly used for anxiety relief.

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