A medicinal alkaloid, galantamine was first developed in Bulgaria in 1959 and is processed from the leaves of the plant Galanthus Caucasius. It is typically prescribed for disorders such as myasthenia, and has been approved by the FDA as an agent to assist in the prevention of diseases such as Alzheimer’s. It is a popular nootropic for the use of enhancing a user’s memory and intellectual potential, and is available as both an over the counter and prescription supplement.



Galantamine affects the body in two ways:

1) It blocks specific enzymes and enzymatic activity inside of the brain.
2) It regulates synaptic sites that are responsive to the compound acetylcholine.

In the first segment, galantamine stops the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine. Because acetylcholine directly affects the intensity at which neurons communicate with one another within the brain, this prevention ensures that the central nervous system remains in optimal condition for the enhancements of cognitive processes, specifically by gradually increasing levels of acetylcholine. In the second, galantamine regulates synaptic sites called nicotinic receptors found on brain cells. These sites work with acetylcholine to assist in the boosting of mental capabilities, and galantamine helps to keep their numbers and structural integrity intact within the brain. This two part process increases the user’s learning potential by making them more receptive to information via a boost in memory and concentration. Sometimes a person’s sensory perception is impacted as well, enhancing what they can see and hear for the benefit of their learning.


Generally, doses in-between 4 and 24 mg per day are acceptable for most users, but a more in depth opinion from a qualified physician would ensure that the appropriate levels of consumption are considered for the best results.


For elevated results, Galantamine can be used in conjunction with cholinergic supplements such as Alpha GPC or Citicoline. Members of the Racetam family, such as Piracetam or Aniracetam, also make fine partners in a nootropic stack.

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